Karen Foster has lived a quiet suburban life until the day her husband leaves her because she’s “no fun.” On a whim, Karen and her two best friends, Mixie and Polly, decide to break out of their McMansion comfort zones and backpack their way through Europe like carefree college students. Mixie feels invisible to her workaholic husband and Polly feels unappreciated by her longstanding boyfriend, who refuses to consider marriage in the wake of a nasty divorce. After fifty years, Karen finally reveals herself, not just to her friends, but also to her long-suffering self. She slowly sheds her uptight demeanor and need for control and allows herself to live.