Best friends Kayla Falk, an engineering student, and Olivia Bellamy, who is studying nursing, are nearing the end of their college career when terrorists attack their university. Through a combination of cleverness, bravery, and luck, the two manage to foil the deadly plot. A mysterious man from the United States government, Mr. Hightower, sees their potential and attempts to recruit Kayla and Olivia for a program to take on ISIS. They initially refuse, but another terrorist attack that strikes close to home pushes them to change their minds and join the Azrael Initiative.

After several months of hard training, the two women are dropped into Al-Raqqah, the capital of ISIS, in Syria. Once there, they must blend in with the locals as they strike from the shadows to kill ISIS leaders, destroy their facilities, and free captives. As Americans deep within enemy territory, they know that they will be killed if discovered. As women, they also know that they would suffer before death. Walking the line between vengeance and justice strains their relationship. As they work to resolve their differences, the symphony of brutality around them ultimately pushes them closer together and forges them into the warriors that they were meant to become.